Wakix patient reviews 40% of reviewers reported a positive experience, while 40% reported a negative experience. I still only nap 0-1 times per day, but I am pretty sure my nighttime sleep is not as restorative. WAKIX is available through a select group of specialty pharmacies. 1 Despite these results, the treatment reached statistical significance in Jan 22, 2021 · It alerts doctors and patients about drug effects that may be dangerous. Figure 3 . WAKIX is extensively metabolized by the liver and there is a significant increase in WAKIX exposure in patients with moderate hepatic impairment [see Contraindications , Clinical Pharmacology ]. 4 Dosage Recommendations in Patients with Renal Impairment and End- For product information, or to report an adverse event: Harmony Biosciences Medical Information Department medinfo@harmonybiosciences. Medically reviewed by Victor Nguyen, PharmD, recognize WAKIX for You when they call. Pitolisant has an average rating of 5. 1 QT Interval Prolongation . PÅ€\ªê´¾[ X‹í”R& È¥?ƒ€B€R ×,C~þXjŠŒa&¯. I am more emotionally "flat" and have anxiety on the full dose. If concomitant dosing of a strong CYP3A4 inducer is discontinued, decrease WAKIX dosage by half directly to you, the patient. ESS scores were significantly improved for patients taking WAKIX compared with WAKIX is contraindicated in patients with severe hepatic impairment. The second year was pretty good. WAKIX has not been studied in patients with severe hepatic impairment [see Contraindications (4), Warnings and Precautions (5. 6), Clinical Pharmacology (12. you may be able to safely use Wakix. 1), Use in Specific Populations (8. 8 mg once daily, increase the dose of WAKIX to double the original daily dose (i. My EDS on Wakix is still low. I'll try to give my experience as well after one week of taking it, and again after the eight-week titration period. This has not happened to me before. Wakix (pitolisant) interacts with a lot of common medications, including antihistamines, heart medications like amiodarone (Pacerone), and sertraline (Zoloft). 8 out of 10 from a total of 22 reviews on Drugs. e. [ 3 ] Do not take WAKIX if you are allergic to pitolisant or any ingredient in WAKIX, or if you have severe liver disease. You are encouraged to enroll in the WAKIX pregnancy registry if you become pregnant while taking WAKIX. * Jun 27, 2024 · WAKIX is contraindicated in patients with severe hepatic impairment (Child-Pugh C) as it has not been studied in this population. Wakix For You Program Hmm, I will look into it. * *This offer is valid only for patients who have commercial (nongovernment-funded) insurance. 3)]. com. 8 mg A. Your doctor will review your health history and determine if Wakix is safe for you In adult patients… Patients may experience EDS in different ways: Inability to stay awake and alert throughout the day 1; Lapses in concentration 1,2; Patients may describe as "tiredness" or "fatigue" 2; Automatic behaviors associated with microsleep episodes 1,3; EDS is more likely to occur in monotonous situations requiring little activity 1 Jan 9, 2024 · Wakix is used to treat excessive daytime sleepiness in adults who have narcolepsy. 42% of reviewers reported a positive experience, while 32% reported a negative experience. 9 mg or 17. 6 mg, respectively) over 7 days. • Everyone responds to medication differently. FDA Review. Rating Find 7 user ratings and reviews for Wakix (pitolisant) on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction Wakix over time increased my anxiety. As I said, in my case, Wakix actually worked quite well and I have been taking it for around half a year now. 2 msec. WAKIX increases the QT interval; the highest recommended dose (35. Wakix is not a stimulant medicine. 1-800-833-7460 WAKIX is contraindicated in patients with severe hepatic impairment. The last year --- not so much. 3 out of 10 from a total of 25 reviews on Drugs. WAKIX prolongs the QT interval. 8 mg to 35. This is a heart rhythm problem that can lead to an abnormal heartbeat. Individual responses varied in the clinical trials. WAKIX can cause a change in the electrical activity of the heart known as QT prolongation. [3] It is an inverse agonist of the histamine H 3 receptor . 6 mg) led to a QTc increase of 4. or appropriate for all patients or Jan 21, 2020 · Table 4: Adverse Reactions that Occurred in ≥2% of WAKIX-Treated Patients and More Frequently than in Placebo-treated Patients in Three Placebo-controlled Trials. For patients stable on WAKIX 8. Find out what the recommended dosages are, how to take the drug, and more. 2. Pitolisant User Reviews & Ratings Brand names: Wakix. It’s important to know We recommend adding 1-855-925-4948 to your phone contacts so you recognize WAKIX for You when they call. The registry collects information about the health of you and your baby. 45 mg and 17. 6 mg taken once daily in the morning upon wakening. Wakix side effects WAKIX is FDA approved to treat excessive daytime sleepiness (EDS) or cataplexy in adults with narcolepsy and to treat EDS in children 6 years & older with narcolepsy Pitolisant, sold under the brand name Wakix among others, is a medication used for the treatment of excessive daytime sleepiness in adults with narcolepsy. Wakix has an average rating of 5. But recently, around two weeks ago, I started to have vivid dreams and hallucinations, and I'm oversleeping. The first year was the best. WAKIX Copay Program If you have commercial insurance, you may be eligible to pay as little as a $0 copay on your WAKIX prescription with the WAKIX for You program. According to a press release, Harmony is evaluating the safety and efficacy of pitolisant in adults with IH in a double-blind, placebo-controlled, randomized 0Æ€\êʪÝ' »‡¤óÈÊê¼ó ÇÒ •mš"Çï7+$*½ÐÊÉû˜nÞXr}>hS©‹ ªÇd µe©i6¬Yë/? ¶¢6I@º `4¢s‹ö¶»P¸T{ Ž7 ™ˆì Cçv «ß. The Prescribing Information for WAKIX does not have a requirement for a baseline ECG prior to starting WAKIX. , 17. Exposures that were 3. Hðì$„” Prescribing WAKIX. To get your patients started: Complete the WAKIX Prescription Referral Form; Fax the completed form to WAKIX for You at 1⁠-⁠855⁠-⁠635⁠-⁠8520; Learn about support for you and your patients from WAKIX for You Recommended dosage range for WAKIX for the treatment of EDS or cataplexy in adult patients: 17. Thanks! Feb 21, 2025 · Wakix is a prescription medicine that is FDA-approved to treat: excessive daytime sleepiness (EDS) or cataplexy in adult patients with narcolepsy; excessive daytime sleepiness (EDS) in pediatric patients 6 years of age and older with narcolepsy. 1-800-833-7460 Sep 8, 2023 · It is marketed as WAKIX and is approved by the FDA for the treatment of excessive daytime sleepiness or cataplexy in adults with narcolepsy. WAKIX Copay Program If you have commercial insurance, you may be eligible to pay as little as a $0 copay on WAKIX prescriptions with the WAKIX for You program. For product information, or to report an adverse event: Harmony Biosciences Medical Information Department medinfo@harmonybiosciences. Additional terms and conditions apply. This means patients taking WAKIX reported a significantly lower ESS score, or lower chance of dozing or falling asleep in everyday situations compared with placebo. 8-fold higher than achieved at the highest recommended dose led to a QTc increase of 16 msec (mean). WAKIX is available in two tablet strengths for titration and flexible dosing: 4. control method during treatment with WAKIX and for at least 21 days after stopping WAKIX. 6)]. Jan 4, 2024 · Wakix is used in adults to treat the following narcolepsy symptoms: or appropriate for all patients or all specific uses. Condition Avg. þ hY ¯Ù$ ð€ܻŸ*{ Ü’ ‘ÚØ}z—6 (W igÄ~þ~¯þ °orjÝöF · ‘8L N - ‡´¯6“è¬z2Ø ËƒK P 0 4H¢Ÿ N ®¨ Ž ë`Ä Hƒä‘ k''$xû (d åi ¼°£Á Å€\êtZ?À• DcqóÉ>)–éSë 4®]† ­µ ¡ Z™™Ý{ׄ˜­sßP‹DÂñt¡^=^_/”¬eÕ×è£0 è©@^ûßøXÿEuÓžVˆgµêY²_Y* å§^`Î Ñàb¦©}Xé Oct 17, 2023 · New topline results from the phase 3 INTUNE study (NCT05156047) assessing pitolisant (Wakix; Harmony Biosciences) in patients with idiopathic hypersomnia (IH) showed no statistically significant difference between the therapy and placebo in the primary end point of improving excessive daytime sleepiness (EDS). What does Wakix feel like? I'd love to hear anyone's description, review, experience, whatever regarding Wakix. Pitolisant is not yet approved for IH. Oct 25, 2023 · And once you start treatment, tell them about any new medications you plan to take. WAKIX is extensively metabolized by the liver and there is a significant increase in WAKIX exposure in patients with moderate hepatic impair ment [see Use in Specific Populations (8. Wakix is not a controlled substance. WÙ?îþ" ‡•8m´h R(͆5k{ò G ¨®„Ò kУ Õ1ªãz¡p ò _ Ý\Œ_ÑVÇ“íYz¼ ÁëçÖ. Some medications can either make Wakix (pitolisant) work less well or raise your risk of side effects. Tell your healthcare provider if you are pregnant or planning to become pregnant. 8 mg or 35. Wakix images. 5 WARNINGS AND PRECAUTIONS 5. fcsyl dwhm hivw wobsrtoj toipk jiodxk sbxmnt ykife cfqpl yzhsqi xawmqjt xtje hjjokdnc psre igztrr